Intranasal Boosting with Spike Fc-RBD of Wild-Type SARS-CoV-2 Induces Neutralizing Antibodies against Omicron Subvariants and Reduces Viral Load in the Nasal Turbinate of Mice

The emergence of new immune-evasive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and subvariants outpaces the development of vaccines specific against the dominant circulating strains.In terms of the only accepted immune correlate of protection, the inactivated whole-virion vaccine using wild-type SARS-CoV-2 spike induces a

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Mechanical Responses of Slurry Shield Underpassing Existing Bridge Piles in Upper-Soft and Lower-Hard Composite Strata

With the development of urban metro systems, shield tunnels that pass through existing bridge pile foundations have become an inevitable engineering problem.Therefore, ensuring the stability of the strata and existing bridge piles during tunnel construction is a common goal in engineering practice.Currently, research on the mechanical responses of

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Changes in the Skin Proteome and Signs of Allostatic Overload Type 2, Chronic Stress, in Response to Repeated Overcrowding of Lumpfish (Cyclopterus lumpus L.)

Lumpfish (Cyclopterus lumpus L) is a North Atlantic species harvested for its roe and increasingly used as a cleanerfish in Atlantic salmon (Salmo salar L.) farming to remove salmon louse (Lepeophtheirus salmonis).In aquaculture, the health and welfare of fish depends on optimal levels of several biotic and abiotic factors.Crowding, a common abioti

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Mycobacterium avium (MAC) lung disease in post-COVID-19 bronchiectasis: a need for caution as a potential risk factor for MAC infection

Abstract Bronchiectasis due to previous tuberculosis is known to precede Mycobacterium avium (MAC) lung disease.Coronavirus disease 2019 (COVID-19) is an emerging infectious disease, and residual bronchiectasis following COVID-19 is common as well as tuberculosis.However, there have been no reports documenting MAC lung lolasalinas.com disease secon

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